IN RESPONSE TO COVID-19:  The health and well-being of everyone involved in our mission is important to us. We have made the decision to make some changes to our normal operating procedures in response to the coronavirus (COVID-19).

All Case for Smiles outreach and events (ex: group sewing events, in-person fundraising events, school and company engagements) are postponed indefinitely. The packaging of pillowcases is halted at this time but we anticipate our chapter coordinators will be able to resume packaging pillowcases in June.

We recognize that this will temporarily impact the services Ryan’s Case for Smiles provides but we believe that this is the right course of action for our organization, volunteers patients and families we serve.

Thank you for your support and understanding during these unusual and difficult circumstances.


A sampling of masks for BAYADA

Please join our efforts in sewing masks for BAYADA pediatric nurses nationwide. A total of 5,000 masks are needed and 1000 for the Philadelphia/New Jersey/Delaware region.  These nurses care for medically complex children, many of whom are ventilator dependent.  This request is urgent for nurses to wear when visiting patients and families who have not been exposed to COVID 19. The masks will be used immediately upon receipt.  Click here to download a pdf with instructions and a link to a video tutorial.  Completed masks can be mailed to:  295 E. Swedesford Road, #396, Wayne, PA  19087. Thank you for your support!


With your help we exceeded our goal of 5,000 masks. Thank you!

  • Percent to Goal 100% 100%

Masks completed by Case for Smiles Chapters across the country! Amazing work!


Help children and families cope with the traumatic stress of illness and injuries by donating your time. The secret to our success is the strength of the thousands of volunteers around the world giving their time to help kids feel better to heal better. We want you to join our team! It is not about money, it is about making a difference.  Working together we can accomplish even bigger things.


We can’t get enough bright, cheery pillowcases. It is easy to do and only takes a few minutes. Click below for simple and fun instructions for creating your own whimsical pillowcase:

How To Sew A Pillowcase Directions (click here)

***It is important to wash the fabric before sewing pillowcases and please do not use scented detergent or dryer sheets. *** Please be sure to include a note with your name and address so we can thank you properly.

What kind of fabric can I use to sew pillowcases?

  • Fabric needs to be 100% cotton. Please do not use fabric with glitter.
  • Remember to use fun, colorful novelty prints!
  • Check with local coordinator for local hospitals specific requirements. For example: some hospitals do not allow flannel and red pillowcases tend to bleed. Some hospitals also do not accept holiday themed pillowcases.
  • We do not accept ‘No-sew pillowcases’. See PDF Guide for full list of guidelines.


Throughout the month of September each year, Ryan’s Case for Smiles hosts a Miles of Pillowcase Smiles campaign. The goal is to complete a minimum of 44,000 pillowcases, one for each child in treatment for cancer.


CLEM MURRAY / Philadelphia Inquirer

Gather the team and get ready for an action packed time with a philanthropy twist! Each corporate team building event is custom tailored for your organization, helping to strengthen the collaboration between team members while giving back to the local community. Participants will engage in activities that promote stress reduction and collaboration, in between the creation of coping boxes. Each coping box created will provide stress reduction activities and tips to siblings and caregivers of children with life changing illnesses and injuries, treated at local hospitals.



We would love to partner with you to host a successful philanthropy event to support us in helping kids feel better to heal better. There are many ways for individuals, schools and businesses to get involved. Please contact us to get your event started.

  • PJ Day
  • Miles for Smiles Run
  • PajamaThon (dance marathon)
  • Wall of Smiles
  • Jeans Day
  • Bag Bingo
  • Sports Tournament
  • Poker Night
  • Talent Show
  • Bake Sale
  • Canning


We can’t do anything without you. Please help us support kids to feel better, to heal better.

Sadly the stream of sick children never ends, while the costs of fabric and materials have tripled over the past few years. Like so many across the country, volunteers have struggled with job losses and economic hardship, making it more difficult for them to continue to donate pillowcases. The average cost of a pillowcase is $11.00 (as determined by auditors Torrillo & Associates, LLC). Individual donations and grants from organizations have helped defray some of the costs but we have found we cannot continue to meet the needs of the children without additional funding. If you would like to make a contribution, please click the Donate button below. For information on how to make a gift of stock or appreciated mutual fund shares, please click here.




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Select Your Area from the dropdown list to find your local coordinators and dropoff points.